Jamestown

Jamestown, Virginia is the location of one of Thalia's, Luke's, and Annabeth's old safehouses.

The Sea of Monsters
Percy, Annabeth, and Tyson go to Annabeth's, old safehouse in order to avoid being seen by a U.S. Coast Guard naval ship. Annabeth says that the safehouse was once used by her, Thalia, and Luke while they were trying to avoid monsters, although now Luke probably doesn't care that it's still there. The safehouse contains many demigod provisions such as weapons, nectar, ambrosia and others.

Percy sends Tyson to find donuts for them to eat so that he can be alone with Annabeth in the safehouse. When Tyson returns, he is excited and tells them that he has found donuts as Percy had told him to. Annabeth and Percy are surprised by this and ask him how he had found them. Tyson tells them that he had gone to a Monster Doughnut store nearby, which was connected to a Hydra. Tyson was able to buy doughnuts because he is a monster whereas a demigod would have gotten killed. The group is then attacked by a Hydra, and narrowly escape by being saved by Clarisse.

The James River
The James River is a site where Thalia and Luke created a safe house before they found Annabeth.